Frownies Launches NEW Apple Serum with Stem Cell Technology!

Frownies, the home of the Original Wrinkle Patch, has expanded its skincare line beyond its wildly popular Frownies Facial Patches to include Frownies Apple Serum with plant-based stem cell technology. 

To better understand how the stem cell technology works, it is helpful to learn the basics of stem cells. Stem cells are special cells, found in all multi-cell organisms, that have the ability to mature into any type of cell. There are two types of stem cells – embryonic (pluripotent) stem cells and adult (somatic) stem cells. Embryonic stem cells can develop into any type of cell in the entire body; whereas, adult stem cells can only mature into a few different types of cells within the organ they are a part of. Adult stem cells are important for the repair and regeneration of tissues in the body.  

Stem cells for Frownies Apple Serum are harvested from the Uttwiler Spätlauber apple, a type of apple native to Switzerland that is known for its amazing longevity. This Swiss apple has an extended shelf-life and can maintain freshness without wrinkling and withering months longer than other types of apples. Scientists discovered that the apple’s longevity is due to its specialized stem cells. 

The apple stem cells from the Uttwiler Spätlauber apple have been shown to provide extensive benefits when applied to human skin. In the presence of apple stem cells, human skin stem cells (adult stem cells) showed an increase in numbers, protection against UV damage, and maintained function for longer periods of time. And these microscopic changes at the cellular level directly translate to improved skin texture at the macro level – Applying apple stem cells directly on the skin showed a decrease in wrinkles around the eyes.  

In research, these apple stem cells have been shown to:

  • Reduce wrinkle depth in the crow’s feet around eyes (Household and Personal Care TODAY n.1/2009)
  • Improve skin smoothness as shown in digital images (Household and Personal Care TODAY n.1/2009)
  • Stimulate the proliferation of skin stem cells (Phytochem Rev (2008) 7:599-605)
  • Protect skin stem cells from UV radiation damage (Phytochem Rev (2008) 7:599-605)
  • Maintain function of skin stem cells even in advanced age (Cosmetics & Toiletries Vol 125, No. 5/May 2010)

Apple stem cells may be used to repair the skin and enhance the skin’s natural ability to heal and regenerate.

To use our serum with this revolutionary ingredient, apply Frownies Apple Serum after cleansing the skin. The serum has a silky texture which absorbs into the skin quickly and may be applied under Frownies Facial Patches without interfering with the adhesive of the patches.  It is recommended to apply other hydrators and moisturizers overtop of Frownies Apple Serum. 

The serum is packaged in single-dose ampoules to maintain potency without added preservatives. In addition, the ampoule packaging is made from biodegradable plant-based packaging, making it environmentally friendly by limiting excessive waste. 

Product highlights:

  • Over 80% active ingredients (apple stem cells)
  • No preservatives
  • No added fragrance
  • Safe for use during pregnancy and breastfeeding
  • Can be applied to skin anywhere on the body including neck, hands, and decolletage 
  • Single-dose, biodegradable packaging

Learn more about Frownies Apple Serum in this interview on Instagram with Frownies Director of Brand Strategy Helen Morrison and Frownies CEO Kat Wright.


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The information provided on this website is intended solely for educational purposes and should not be construed as medical or dermatological advice. At Frownies, we recognize that individual skin responses to treatments and skincare products vary. Testimonials shared represent personal experiences and may not reflect the outcomes of all users, as results depend on numerous factors such as consistency, skin type, age, lifestyle, and more.

We strongly recommend consulting with your healthcare provider or dermatologist before incorporating any new skincare regimen, including Frownies products, especially if you have pre-existing medical conditions or specific skincare concerns.

Thank you for prioritizing your health and well-being.