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The Frownies

Apple Serum-Malus Domestica-Apple Stem Cell Extract

Apple Serum-Malus Domestica-Apple Stem Cell Extract

Regular price  $39.95
Regular price  Sale price  $39.95
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15-1ml ampoules for easy application and less preservatives!

Love this serum!

I’ve been using the Frownies Apple Serum for over a month twice a day and really love it! I feel like I’m starting to see a difference in the fine lines around my eyes. Love how the serum feels and how hydrating to my skin it is. Will keep this as a staple in my skin care.


SOF Journal article on Apple Stem Cell

An Apple a day Stem cell research    

Fruit derived stem cell for skin care                                                            


Wash your face with the Frownies PH Balancing Face Wash and then apply a pea size amount of Frownies Apple Stem Cell Serum concentrating on the area around the eyes, mouth, neck, or anywhere where you notice more fine lines and thinning of the skin.

After applying the Apple Stem Cell Serum pop the top back on the ampule for later use.


Malus Domestica is a unique apple that grows in the Alps of northern Switzerland. Once picked the apple stays fresh months longer than ordinary fruit without shriveling or wrinkling.

Studies show that apple stem cells decreased wrinkles; boosting production of human stem cells. When tested in vitro (in a lab), the apple stem cell extract was applied to human stem cells and was found to increase the number of the stem cells in the culture.

Apply the Apple Stem Cell Serum to the skin on the face and neck twice daily (morning and evening). We recommend using the Apple Stem Cell Serum under your daily moisturizer or night crème as an enhancement to the other hydrating ingredients.

The Apple Stem Cell Serum is packaged in a biodegradable ampule. The small ampule prevents the need for additional preservatives and ensures the potency of the ingredients.


Malus Domestica Fruit Cell Culture Extract, Hydroxyethyl Urea, Carnosine, Lecithin, Trehalose, Sodium Lactate, Allantoin, Tremella Fuciformis (Mushroom)Extract, Avena Sativa (Oat) Kernel Extract, Portulaca Oleracea Extract.


Q: What's the difference between the Apple Stem Cell Serum and the Frownies Skin Serum?

A: The Frownies Skin Serum is a facial oil with high concentration of naturally occurring Vitamin C and Vitamin meant to lock in moisture and provide beneficial antioxidants to the skin. The Apple Stem Cell Serum is meant to fight the affects of aging and improve stem cell production in the skin. Frownies Skin Serum and Frownies Apple Stem Cell Serum are complimentary and should be used together for greatest impact!

Q: How many ampules come in a box?

A: There are 15 ampules in each box.

Q: How many uses can I get from one ampule?

A: If you are applying the serum to your face and neck you can use 1/2 an ampule in the morning and 1/2 at night. If you are concentrating only on the area around the eyes and mouth you might be able to get 3 or 4 uses out of one ampule (using a few drops at a time).

Q: How long will it take to see results?

A: When it comes to skin care it can take up to 12 weeks for full cell turnover so remember that consistent use over time will produce the best results. Be consistent using the Apple Stem Cell Serum twice a day for best results.

Q: Do I need to use a moisturizer after applying the Apple Stem Cell Serum.

A: Yes, we recommend using the Frownies Moisturizers for Face and Neck.


We are so confident you will see results before the end of your first month of continuous use of our Facial Patches, that if your frown lines do not show any signs of improvement, we will refund purchase.

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Customer Reviews

Based on 52 reviews
Jennifer K
Great stuff!

I could definitely notice and improvement right away, and others could too!

Improves Eyelid Milia (!!!)

I'm susceptible to milia bumps due to some autoimmune issues and the only ones I haven't found a solution for are the ones that form on my eyelids (thanks hooded eyes lol) because I dont want to put retinoids or acids near my eyes. Enter this serum! I gave it a try after reading a review noting that it helped get rid of a bump near the reviewer's eye. After about two months (one box) of almost daily use (twice a day when I remember) the largest bump came to a head and I could **carefully** pop/extract it myself. The other bumps seem to be slowly diminishing in size. I'll keep purchasing and if it helps keep fine lines to a minimum (I use it all around my eyes and mouth) then that's great too!

Note: always be careful about what you put around your eyes, folks. This isnt the intended use for this product--it's just happened to work for me this way. :)

Hi Allison, thanks so much for your review. We're so glad that the Apple Serum has helped you out! We appreciate your disclaimer about the Apple Serum not being intended for milia bumps -- we'd have to agree with this!! However, we're always happy to hear when customers experience benefits outside the normal expectations. Because our products are made from natural ingredients, it's usually safe to play around with using them for other things, but of course, we'd always recommend talking with your health care provider if you have any questions or concerns. Thanks again for sharing!! - Frownies Customer Care

Eco friendly and effective!

Love that these capsules are biodegradable and that def influenced my decision to try them. I’ve been using them only under my eyes for about 4 mos. One capsule lasts like a week and I use a drop under each eye twice a day. I def notice a difference with the fine lines around my eyes. I think I might start using it on my face to improve firmness. I’m def sticking with these. I use vit c serum in the morning but no retinol (for now) so I am certain this product is working since I’m not using anything else near my eyes.

Thank you for your review, Bansari! We're so happy you're enjoying the Apple Serum. It is such a powerful product packed into those ampoules! It's great to hear you're getting it to stretch so far, too. Our entire site is 20% off for the month of November, so it's a great time to stock up if needed! If you have any questions, please don't hesitate to message us on We appreciate you!! - Frownies Customer Care


I have been using this product for a few months now. I love how quickly it absorbs. With it being packaged in ampules, you have just the right amount of product with out using it up too quickly. A little does go a long way, and it absorbs VERY quickly. I apply it around my eyes, my smile lines, my forehead and neck. I think it even helps heal my skin if I've had some breakouts. I have noticed some reduction in the appearance of fine lines. I am very expressive, so they aren't completely gone, but as long as I am hydrated properly, I notice the difference very much. My skin looks very glowy after applying. I'm hoping over time with continued use I will see more and more results. Like someone else already said - It goes well under make up as long as you let it dry first (and it dries very fast). I like that it doesn't make me breakout like a lot of other products do, especially on my neck where that skin seems to be very prone to pour clogging. I apply it once in the morning and once at night. Even if i forget, I always apply it at least once a day. I wish I could buy this in bulk!

Thanks for your review, Cerah! We're so happy you tried our Apple Serum and that you enjoyed the results you experienced. It's a powerful product packed into those ampoules! While we don't offer it in bulk, all of our products are 20% off right now for the month of November, so it's a great time to stock up on the item if you're interested! And if you have any questions, please don't hesitate to message us on or email Many thanks, Frownies Customer Care

Kara H
Love it

I really like the smell and texture of this serum. It's nice and light and blends well with other moisturizers, serums and works fine under makeup!

Hi Kara, thanks so much for your review! We're so happy you're enjoying the Apple Serum. We love how hydrating it is, even for being so lightweight. We hope you'll continue to enjoy it. If you ever run into any questions, please don't hesitate to message us on Many thanks, Frownies Customer Care