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Apple Serum-Malus Domestica-Apple Stem Cell Extract

Apple Serum-Malus Domestica-Apple Stem Cell Extract

Regular price  $39.95
Regular price  Sale price  $39.95
Sale Sold out

15-1ml ampoules for easy application and less preservatives!

Love this serum!

I’ve been using the Frownies Apple Serum for over a month twice a day and really love it! I feel like I’m starting to see a difference in the fine lines around my eyes. Love how the serum feels and how hydrating to my skin it is. Will keep this as a staple in my skin care.

Game changer!

I have noticed a synergistic effect of using the Apple Serum and the Frownies in combination.
I started combining the two recently after receiving my apple serum. I put it on in the morning and the night. I like the rich texture of it and i feel it going into my little cracks and lines and hydrating them. I will be 50 this year and I truly think I have seen such a hug improvement since beginning my “frownies journey”. --Anastasia


SOF Journal article on Apple Stem Cell

An Apple a day Stem cell research    

Fruit derived stem cell for skin care                                                            

How to apply for best results

Wash your face with the Frownies PH Balancing Face Wash and then apply a pea size amount of Frownies Apple Stem Cell Serum concentrating on the area around the eyes, mouth, neck, or anywhere where you notice more fine lines and thinning of the skin.

After applying the Apple Stem Cell Serum pop the top back on the ampule for later use.

Understand the details

Malus Domestica is a unique apple that grows in the Alps of northern Switzerland. Once picked the apple stays fresh months longer than ordinary fruit without shriveling or wrinkling.

Studies show that apple stem cells decreased wrinkles; boosting production of human stem cells. When tested in vitro (in a lab), the apple stem cell extract was applied to human stem cells and was found to increase the number of the stem cells in the culture.

Apply the Apple Stem Cell Serum to the skin on the face and neck twice daily (morning and evening). We recommend using the Apple Stem Cell Serum under your daily moisturizer or night crème as an enhancement to the other hydrating ingredients.

The Apple Stem Cell Serum is packaged in a biodegradable ampule. The small ampule prevents the need for additional preservatives and ensures the potency of the ingredients.

We are looking for sustainable packaging solutions, and terms such as recyclable, compostable, and biodegradable are commonly used together, often interchangeably, they refer to different processes.
Biodegradable plastics are not compostable they do decompose much faster than their traditional counterparts which may take hundreds of years to break down. They seem, therefore, a more environmentally friendly solution.
The conversation about which packaging (recyclable, biodegradable or compostable) is best for the environment is ongoing and there’s no single answer to this question. All of these solutions come with their own benefits and limitations but are Frownies step forward in considering more sustainable alternatives to standard packaging.

Ingredients from the Earth

Aqua, Malus Domestica Fruit Cell Culture Extract Glycerin, Peg-2m, Butylene Glycol, Hydroxyethyl Urea, Carnosine (peptide), Xanthan Gum,Lecithin, Trehalose, Sodium Lactate, Allantoin, 1,2-hexanediol, Tremella Fuciformis (Mushroom) Extract, Polyacrylate Cross- Polymer-6, Pentylene Glycol, Avena Sativa (Oat) Kernel Extract, Portulaca Oleracea Extract, Propylene Glycol, Lactic Acid.

Many of the ingredients are from around the world and we have a certificate of analysis for every ingredient certifying its purity and stability.

The lab where the product is manufactured has a Good Manufacturing Process Certification has passed 1SO22716 which gives guidelines for the production, control, storage and shipment of cosmetic products. These guidelines cover the quality aspects of the product, The lab has passed US FDA Cosmetic Good Manufacturing Practice Certification as well.

All Frownies products are the highest quality ingredients and manufacturing processes.

You ask and we answer FAQ'S

Q: What's the difference between the Apple Stem Cell Serum and the Frownies Skin Serum?

A: The Frownies Skin Serum is a facial oil with high concentration of naturally occurring Vitamin C and Vitamin meant to lock in moisture and provide beneficial antioxidants to the skin. The Apple Stem Cell Serum is meant to fight the affects of aging and improve stem cell production in the skin. Frownies Skin Serum and Frownies Apple Stem Cell Serum are complimentary and should be used together for greatest impact!

Q: How many ampules come in a box?

A: There are 15 ampules in each box.

Q: How many uses can I get from one ampule?

A: If you are applying the serum to your face and neck you can use 1/2 an ampule in the morning and 1/2 at night. If you are concentrating only on the area around the eyes and mouth you might be able to get 3 or 4 uses out of one ampule (using a few drops at a time).

Q: How long will it take to see results?

A: When it comes to skin care it can take up to 12 weeks for full cell turnover so remember that consistent use over time will produce the best results. Be consistent using the Apple Stem Cell Serum twice a day for best results.

Q: Do I need to use a moisturizer after applying the Apple Stem Cell Serum.

A: Yes, we recommend using the Frownies Moisturizers for Face and Neck.

Our Promise

We are so confident you will see results with continuous use of Frownies wrinkle patches and skin care products, that we will refund the purchase price (excluding shipping and handling paid by B&P Company Inc) if you're not happy with the benefits. 

Simply return your product within 30 days of purchase. All returns must be in their original package, and accompanied by the original invoice from Frownies.

You may call customer service at 800-648-6891 with any questions. Our business hours are from 8:00 am to 4:00 pm EST Monday through Thursday and 8:00 am  to 12:00 pm EST on Friday

Please address all returns to:

Frownies Guarantee
ATTN: Customer Service 
97 Compark Road
Centerville, OH 45459
We strongly recommend that you seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition and your skincare.
The information presented on FROWNIES website is intended for general education purposes only and should not be relied upon as a substitute for professional and/or medical advice.
The contents of the FROWNIES website are for information purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

 Please review our Terms of Service

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Customer Reviews

Based on 66 reviews
Bethany Beachey
Love it!

I love the feel of it. My face feels hydrated. So smooth too!

Hi Bethany, thanks so much for your review! We're so glad you're enjoying Frownies Apple Serum. If you ever have any questions, message us on or email We appreciate you!! - Frownies Customer Care

Diane Smith
Apple stem serum

I love this, and I am actually seeing my brown spot lightening up. This is my second order of this & will reorder. By the way I’ve worn Frownies for 50 years. An original & very happy customer!!

Thank you for your feedback, Diane! We're so glad you're enjoying Frownies Apple Serum. It's a powerful product packed into those ampoules and a little can go a long way. We truly appreciate your many years of business with our small, family-owned company. Please let us know if you ever have any questions or need any assistance. We're available at or Many thanks, Frownies Customer Care

Mary Ann
Apple a day

The apple stem cell serum goes on smooth and is not heavy or greasy. I use it under my daily moisturizer. I will definitely re order this product

Thank you for your feedback, Mary Ann! We're glad to hear that you like our Apple Serum. If you haven't yet, come join us on and All our best, Frownies Customer Care

suzi elliott
Love the Apple Serum

Ordered this last month and while I was leary of the price these little vials are magic! So worth it! Don’t wait and order now!

Hi Suzi, thanks for this feedback! We love our Apple Serum and we're excited you do, too!! Come join us on and if you haven't already. Cheers, Frownies Customer Care

Do not disclose
I love the apple serum

The apple serum is amazing. I use it morning and night. However, I was really disappointed when I purchased two boxes and thought it automatically included the free eyegels because I purchased it during that deal. I didn’t realize I had to include the code. So love the product will continue using but bummed about the eyegels not being automatically added into my cart. It’s the reason I bought two boxes of apple serum. I thought it would be a good opportunity to try more frownies products to see if it was a good investment.

Hi there, thank you for your review. We're so glad to hear you're enjoying Frownies Apple Serum. We're sorry to hear you missed the December promotion for the free eye gels. While you did need to enter the promo code, it was also only eligible in December and not for January purchases. Be sure to follow us on for future promo announcements or sign up for our newsletters at All our best, Frownies Customer Care